Description of Research Area

A03: Function | Proposed Research Projects (2016-2017)

The Chemotactic Response and Motor Function of a Bacterial Flagellar Motor in a Single Cell

Leader

ISHIJIMA, Akihiko

Graduate School of Frontier Biosciences, Osaka University
URL : http://www.fbs.osaka-u.ac.jp/labs/ishijima/index-E.html

Research Subject

In biological system, macromolecules in the nanometer scale are key players in various physiological functions, including movement and signal transduction. However, these mechanisms were not understood well still. In my laboratory, in order to understand fundamental principle of mechanism of bio molecules, we are developing single molecule measurements and imaging systems that are capable to measure the movements of bio molecules at nanometer, picoNewton scale. Our goal is to determine the mechanism of bio molecules, for example, actomyosin motor, bacteria flagellar motor, signal transduction, and so on, by novel equipments being developing in my laboratory.

bacteria flagellar motor
Grant-in-Aid for Scientific Research (KAKENHI) on Innovative Areas, MEXT, Japan
Synergy of Fluctuation and Structure : Quest for Universal Laws in Non-Equilibrium Systems