Description of Research Area

A03: Function | Proposed Research Projects (2014-2015)

Spatiotemporal Fluctuations in Cell-Cell Interactions Investigated by Scanning Probe Microscopy

Leader

OKAJIMA, Takaharu

Graduate School of Information Science and Technology, Hokkaido University
URL : http://www.ist.hokudai.ac.jp/labo/cell/en/

Research Subject

The mechanical properties of living cells and their mechanical interactions can be strongly associated with maintaining cell structures and cell functions. Direct measurements of the spatiotemporal dynamics and the mechanical interactions are crucial to understand the interplay between their cell structures and functions. In this study, using scanning probe microscopy (SPM) that allows us to probe the spatiotemporal changes in cell mechanical properties at the single cell level, we measure the fluctuations of intracellular mechanical properties and cell membranes and investigate how these cell dynamics influence various cell functions.

Research Partner

SUEOKA, Kazuhisa
Graduate School of Information Science and Technology, Hokkaido University
Grant-in-Aid for Scientific Research (KAKENHI) on Innovative Areas, MEXT, Japan
Synergy of Fluctuation and Structure : Quest for Universal Laws in Non-Equilibrium Systems